The city of Ann Arbor, Michigan, currently has 23 active clinical trials seeking participants for Pain research studies.
Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)
Recruiting
The main objective of the study is to evaluate the safety, performance and clinical benefits of the Persona implant and its instrumentation in primary total knee arthroplasty
Gender:
All
Ages:
18 years and above
Trial Updated:
06/18/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Knee Pain Chronic, Osteoarthritis, Knee, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Varus Deformity, Valgus Deformity, Flexion Deformity of Knee, Avascular Necrosis
Support, Training, and Education for Pain Self-Management Using Podcasts: A Pilot Trial
Recruiting
This randomized Stage 1 pilot trial tests the feasibility of a community health worker (CHW) delivered chronic pain self-management intervention for older adults ("STEP-UP"; Support, Training, and Education for Pain Self-Management - Using Podcasts) in a primary care setting. A total of 40 participants aged 50+ with high-impact chronic pain will be randomized to intervention or control groups. The STEP-UP intervention will feature an educational podcast series teaching core pain self-management... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
06/17/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Chronic Pain
Burst Spinal Cord Stimulation (Burst-SCS) Study
Recruiting
Recently a new form of spinal cord stimulation therapy called burst spinal cord stimulation (Burst-SCS) is available to treat chronic pain. The goal of this study is to learn more about how Burst-SCS works to reduce chronic pain. The study will examine chronic pain patients who have been deemed candidates for Burst-SCS therapy, and who have already been selected to receive a temporary externalized trial of Burst-SCS from their own doctors as part of their standard clinical care for chronic pain... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/14/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Pain, Chronic, Failed Back Surgery Syndrome
Healing Opioid Misuse and Pain Through Engagement (HOPE) Trial
Recruiting
This study is a multisite randomized clinical trial of a treatment designed to reduce pain interference while simultaneously addressing relapse prevention among individuals who have co-occurring chronic pain and Opioid Use Disorder (OUD). This study will recruit approximately 160 individuals who are currently being treated in clinics specializing in the physician management of OUD. To increase generalizability of study findings and increase internal validity of the physician management component... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/11/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Opioid Use Disorder, Chronic Pain
Exparel Injection for Postoperative Orbital Pain
Recruiting
After surgery to remove the eye, either by enucleation or evisceration, patients have variable levels of pain for several postoperative days. Some patients have almost no discomfort while others require significant amounts of oral narcotics and report pain of 10 out of 10 on a numerical rating scale. The current operative standard is to infiltrate the eye socket with 0.5% bupivacaine during surgery leading to several hours of postoperative analgesia. In 2011, Pacira Pharmaceuticals released a bu... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/11/2024
Locations: University of Michigan Kellogg Eye Institute, Ann Arbor, Michigan
Conditions: Pain, Postoperative
Psychosocial Pain Management to Improve Opioid Use Disorder Treatment Outcomes
Recruiting
The purpose of this research study is to look at the effect of programs aimed at helping people manage chronic pain and medication treatment. The program sessions focus on educational information and strategies for pain and medication management. The researchers enroll people who have chronic pain and have recently begun buprenorphine treatment to see if participants could benefit from these programs. This research study will help the researchers learn how to improve current therapies for pain a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: Veterans Affair Ann Arbor Healthcare System, Ann Arbor, Michigan +1 locations
Conditions: Opioid-use Disorder, Medication Assisted Treatment, Chronic Pain
MIVetsCan: Can-Coach Trial (Phase 2)
Recruiting
The goal of the MIVetsCan Can-Coach Trial is to test four coaching sessions to help Veterans with chronic pain use their own cannabis products more effectively to manage pain and related symptoms.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/02/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Chronic Pain
Sensory Testing of Multiple Forms of Spinal Cord Stimulation for Pain
Recruiting
Doctors sometimes treat chronic pain with devices that send mild electrical currents into the spinal cord. This type of treatment is referred to as neurostimulation. A common form of neurostimulation therapy is spinal cord stimulation (SCS). In this study, researchers want to learn more about how SCS affects pain processing and relieves pain. The researchers will examine multiple forms of SCS in chronic pain patients who are receiving SCS from their own doctors as part of their standard of care.... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/29/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Chronic Pain, Failed Back Surgery Syndrome, Complex Regional Pain Syndromes, Neuropathic Pain
A Trial of a Positive Psychology Intervention for Older Adults (RESET) During the COVID-19 Pandemic
Recruiting
The heightened vulnerability to COVID-19 of African American older adults in Detroit, Michigan and other marginalized communities is linked to systemic racism experienced over the life course. Structural inequities also magnify the pandemic's impact on older adults' physical and psychosocial functioning. Many older adults in Detroit, burdened by poor health even before the pandemic, face a downward spiral of increased distress, reduced physical and social activity, and physical deconditioning. R... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
04/23/2024
Locations: University of Michigan, Ann Arbor, Michigan +1 locations
Conditions: Depressive Symptoms, Anxiety, Chronic Pain, Fatigue, Loneliness, Stress, Psychological
Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare
Recruiting
The purpose of this trial is to investigate the efficacy and safety of dapansutrile (OLT1177®) tablets in subjects with an acute gout flare.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/01/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Acute Gout Flare, Gout Attack, Gout Flare, Gouty Arthritis, Gout, Arthritis, Joint Pain
Self-Administered Acupressure for Veterans With Chronic Back Pain
Recruiting
Many Veterans experience chronic pain, with back pain the most commonly reported condition. The Veterans Health Administration (VHA) is moving from reliance on medications to an approach in which non-medication interventions, including complementary and integrative health treatments, are now a first line of care. Acupressure, a Traditional Chinese Medicine technique derived from acupuncture, is emerging as a potentially effective approach for treating several chronic pain conditions and could pr... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/07/2024
Locations: VA Ann Arbor Healthcare System, Ann Arbor, MI, Ann Arbor, Michigan
Conditions: Low Back Pain
MIVetsCan: Cannabidiol (CBD)-Care Trial
Recruiting
This research is studying the effects of cannabidiol (CBD), an active component from cannabis (a.k.a. marijuana), on Veterans' chronic pain. The purpose of this study is to better understand if CBD can improve pain symptoms in Veterans with chronic pain. Eligible participants will be randomly assigned to receive either placebo medication (not active) or CBD during the study period. The study hypotheses: - CBD would improve overall pain symptoms compared to placebo
Gender:
All
Ages:
18 years and above
Trial Updated:
03/06/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Pain, Chronic